Features and Use Notes of Nylon Filter Membrane

Filter membrane general introduction

  1. Chemical Compatibility:
    • Nylon membranes are compatible with a wide range of solvents and chemicals, making them suitable for diverse filtration applications.
  2. Low Extractables:
    • Nylon membranes typically exhibit low levels of extractables, ensuring minimal interference with samples.
  3. Hydrophilic Nature:
    • Nylon is inherently hydrophilic, meaning it has an affinity for water. This property makes nylon membranes suitable for filtering aqueous solutions.
  4. Broad Pore Size Range:
    • Nylon filter membranes are available in a variety of pore sizes, ranging from microfiltration to ultrafiltration, providing flexibility for different filtration needs.
  5. High Flow Rates:
    • Nylon membranes generally offer high flow rates, allowing for efficient and rapid filtration of samples.
  6. Temperature Resistance:
    • Nylon is temperature-resistant, and nylon filter membranes can be used for filtration processes involving both cold and hot solutions.
  7. Mechanical Strength:
    • Nylon membranes exhibit good mechanical strength, making them durable and resistant to tearing during handling.
  8. Biological Inertness:
    • Nylon is biologically inert, making it suitable for applications involving biological samples without interfering with the sample’s composition.

Microporous membranes are indispensable for microbiological testing and some small-scale liquid filtration, and HAWACH offers a wide range of materials, diameters, and pore sizes for use with different types of membrane filters or filter holders.
Microporous filter membranes have a smooth surface, light texture, high porosity, and uniform microporous structure, and therefore have a fast flow rate and are not easily adsorbed. It is used for filtering bacteria and particles in the pharmaceutical industry, production of products, mineral drinks, brewing, watches, and other industrial aspects of water quality, pharmaceutical oil, lubricating oil, fuel oil, and scientific research laboratories.

Nylon filter membrane

The material is aliphatic nylon with good hydrophilicity and resistance to appropriate concentrations of acids and bases. It is suitable not only for aqueous solutions containing acids and bases, but also for organic solvents such as alcohols, hydrocarbons, ethers, esters, ketones, benzene and benzene congeners, dimethylformamide, dimethyl sulfoxide, etc. The pore size selection principle is the same as that of mixed fiber membranes, i.e. the nominal pore size um is used for particulate removal and 0.8um, 0.45um, 1um, 0.22um, 0.1um, diameter: 13mm, 25mm, 47mm, 90mm, 142mm and 293mm for bacteria removal. All the above are available in HAWACH.

If the filtrate has more particles or bacteria, it must be pre-filtered according to the same principles as the mixed fiber membrane. If filtered for a short period of time [a few hours], the product is resistant to formic acid at 20%, hydrochloric acid at 30% hcl and other acids of comparable acidity, and alkali at 3% sodium hydroxide, but if exposed to these concentrations for a long period of time, it will cause the nylon amide bonds to break and the membrane to become brittle.

Before use, the product should be cleaned by soaking it in distilled water and then put in the filter. For the filtration of chromatographic samples or reagents, if the product is aqueous, it should be washed with distilled water and then pre-filtered with distilled water. If the product is organic, it should be soaked overnight in pure toluene and 95% ethanol, pre-filtered with pure toluene and ethanol, and then used after thoroughly washing the membrane. It is significantly brittle after entering the water, but the reduction of strength into organic solvents is lighter, so the use of this product should be 60-100 mesh nylon mesh or metal mesh under the membrane so that there is no risk of membrane breakage.

Use Notes for Nylon Filter Membrane:

  1. Compatibility Considerations:
    • Ensure that the nylon membrane is compatible with the specific solvents and chemicals used in your application. Verify compatibility based on the manufacturer’s recommendations.
  2. Pore Size Selection:
    • Choose the appropriate pore size based on the size of particles or microorganisms you need to retain or exclude. Smaller pore sizes are suitable for fine filtration, while larger pores are used for bulk particle removal.
  3. Pre-Wetting:
    • It is often recommended to pre-wet nylon membranes with a small volume of the intended filtrate before filtration. This helps to eliminate any potential effects of air entrapment and ensures uniform wetting of the membrane.
  4. Filtration Technique:
    • Use the appropriate filtration technique, such as vacuum filtration or pressure-driven filtration, based on your specific requirements and equipment available.
  5. Rinsing and Elution:
    • After filtration, rinse the membrane with a suitable solvent to recover any retained substances. For some applications, elution may be necessary to ensure complete recovery of the filtrate.
  6. Sterilization:
    • Nylon filter membranes are often sterilizable, but the method may depend on the pore size and application. Common sterilization methods include autoclaving, gamma irradiation, or ethylene oxide treatment.
  7. Proper Handling:
    • Handle nylon filter membranes carefully to avoid damage. Use clean forceps or tools when manipulating the membranes to prevent contamination.
  8. Storage Conditions:
    • Store nylon filter membranes in a clean and dry environment. Follow the manufacturer’s recommendations regarding storage conditions, including temperature and humidity.
  9. Application Areas:
    • Nylon filter membranes are commonly used in applications such as sample preparation, microbiological analysis, and clarification of aqueous solutions.

Always refer to the specific recommendations provided by the membrane manufacturer for the optimal use of nylon filter membranes in your laboratory applications.