The Use of Microporous Membrane

Laboratory workers use a membrane to filter two phases. Actually, the membrane is a kind of media. According to different aperture sizes, filter membranes can be divided into the microporous membrane, ultrafiltration membrane, nanofiltration membrane and reverse osmosis membranes. Specifically, the microporous membrane is commonly used in laboratories with an aperture size of 0.1 to 1 micron. Talking about microporous membrane, it is mainly made from refined nitrocotton with moderate cellulose acetate, acetone, n-butyl alcohol, ethyl alcohol, etc. It is important to filter solvent and samples with the microporous membrane in the laboratory, basically, there are two reasonable concerns. One is to protect the chromatographic column and instrument. The other is to prevent pollution from affecting the analysis results. For example, for the ultraviolet detector, if sample concentration is low to a certain degree, the particle will cause serious noise to interfere with normal signals and finally decrease the SNR (Signal to Noise Ratio) and affect the test results.

Choose of Microporous Membrane
PTFE: Apply to all solvent, acid and salt.
Nylon: Apply to the most organic solvent and hydro solvent.
RC: Apply to water-soluble sample and an organic solvent.
PES: Apply to water-soluble sample.

Caution against Using of Microporous Membrane
1. Using a syringe with volume of fewer than 10 ml may cause burst due to high pressure.
2. Different membrane materials will produce different absorption efficiency, but do remember to choose the microporous membrane in accordance with the recommendation in operation specification.